Stroke Trials Registry

Hemodilution

Action
Decreased viscosity may increase cerebral blood flow or oxygen delivery

Status
Early studies have had mixed results but recent studies have failed to demonstrate protective effect.

Trial(s)
= Ongoing
= Completed

Adjusted hypervolemic hemodilution in acute ischemic stroke.

Hemodilution therapy in acute ischaemic stroke

HSS Hemodilution in Stroke Study

IASS-H Italian Acute Stroke Study-Hemodilution

Neurological deterioration under isovolemic hemodilution with hydroxyethyl starch in acute cerebral ischemia.

Randomized Controlled Trial of Hemodilution Therapy in Acute Ischemic Stroke

SSS Multicenter Trial of Hemodilution in Ischemic Stroke

Web Links and Publications

Haemodilution for acute ischaemic stroke.
Cochrane Database Syst Rev. 2000;(2):CD000103

Individualized hemodilution in acute brain infarct using a 20% albumin solution and physiological saline solution.
Ned Tijdschr Geneeskd 1992 Dec 5;136(49):2422-8

Custom-tailored hemodilution with albumin and crystalloids in acute ischemic stroke.
Stroke 1992 Feb;23(2):181-8

Evaluation of long-term outcome and safety after hemodilution therapy in acute ischemic stroke.
Stroke 1992 May;23(5):657-62

Adjusted hypervolemic hemodilution in acute ischemic stroke.
Stroke 1990 Oct;21(10):1429-34

Hemodilution therapy in acute ischaemic stroke.
Neurol Psychiatr (Bucur) 1989 Apr-Jun;27(2):79-90.

GM1 ganglioside therapy in acute ischemic stroke. Italian Acute Stroke Study--Hemodilution + Drug.
Stroke 1989 Sep;20(9):1143-9

Multicenter trial of hemodilution in acute ischemic stroke. I. Results in the total patient population. Scandinavian Stroke Study Group.
Stroke 1987 Jul-Aug;18(4):691-9.

Multicenter trial of hemodilution in ischemic stroke--background and study protocol. Scandinavian Stroke Study Group. Stroke Study Group.
Stroke 1985 Sep-Oct;16(5):885-90.

A randomized controlled trial of hemodilution therapy in acute ischemic stroke.
Stroke 1984 Nov-Dec;15(6):980-9

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