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Stroke Interventions in Clinical Trials
Printable Version
Troxoprodil
CP-101,606

Action
Glutamate receptor antagonist, selective for NMDA receptor NR2B subunit. ((1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol)

Status
Phase II trials for traumatic brain injury or hemorrhagic stroke reported 1999. Phase III stroke trials ongoing.

Trial(s)
  = Ongoing
  = Completed

Web Links and Publications
Pfizer Web Site.
An open-label study of CP-101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral hemorrhage.
Ann N Y Acad Sci. 1999;890:51-8.
A double-blind, placebo-controlled study of the safety, tolerability and pharmacokinetics of CP-101,606 in patients with a mild or moderate traumatic brain injury.
Ann N Y Acad Sci. 1999;890:42-50.

UID: 96

   

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